STEAP1 (Six-transmembrane Epithelial Antigen of Prostate 1, Metalloreductase STEAP1, STEAP, PRSS24)

Größe

£518.00

SKU:: 138392
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-70 from human STEAP1 expressed in E. coli
Klon:: 13H361
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol
Weitere Details:: Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. Applications: Suitable for use in Immunofluorescence/Immunocytochemistry, ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunofluorescence (IC): 1:100 Western Blot: 1:500 Immunohistochemistry (Paraffin): 1:50. Heat induced antigen retrieval in 0.1M citrate buffer, pH 6.0 is recommended Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice