ITK, Active, Recombinant, Human, GST-Tag (Tyrosine-protein Kinase ITK/TSK, Interleukin-2-inducible T Cell Kinase, IL-2-inducible T Cell Kinase, Kinase EMT, T-cell-specific Kinase, Tyrosine-protein Kinase Lyk, EMT, LYK)

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£912.00

SKU:: 137304
Molekulargewicht:: 57
Reinheit:: Purified (~75%)
Lagerbedingungen:: -70°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 100mM sodium chloride, 0.05% Tween 20, 3mM DTT, 10% glycerol.
Weitere Details:: ITK is an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. Source: Recombinant corresponding to aa352-620 from mouse ITK, fused to GST-tag at N-terminal, expressed in Sf9 cells via a baculovirus expression system. Molecular Weight: ~57kD Applications: Suitable for use in the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Specific Activity: ~1pmol/min/ug Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.