Histone H2a, Recombinant, Human (Histone H2A Type 1-A, Histone H2A/r, H2AFR, Histone Cluster 1 H2aa, HIST1H2AA, bA317E16.2)

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£1,085.00

SKU:: 137283
Molekulargewicht:: 14.8
Reinheit:: Highly Purified (~90%)
Lagerbedingungen:: -70°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in 50mM Tris-HCl, pH 8.0, 150mM sodium chloride, 10% glycerol, 1mM PMSF, 1mM DTT.
Weitere Details:: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Source: Recombinant corresponding to aa2-130 from human Histone 2A, fused to His tag at N-terminal, expressed in E. coli. Molecular Weight: ~14.8kD Applications: Suitable for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.