TEN1, Recombinant, Human, aa1-123, His-Tag (CST Complex Subunit TEN1, TEN1 Telomerase Capping Complex Subunit Homolog, C17orf106)

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£544.00

SKU:: 137229
Molekulargewicht:: 16.2
Reinheit:: ~90% (SDS-PAGE)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, 0.15M NaCl, 10% glycerol, 1mM DTT.
Weitere Details:: TEN1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Source: Recombinant protein corresponding to human TEN1, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~6.2kD (146aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMMLPKPG TYYLPWEVSA GQVPDGSTLR TFGRLCLYDM IQSRVTLMAQ HGSDQHQVLV CTKLVEPFHA QVGSLYIVLG ELQHQQDRGS VVKARVLTCV EGMNLPLLEQ AIREQRLYKQ ERGGSQ Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.