Hexyl-4-pentynoic Acid, HDAC Inhibitor (2-(2-propynyl)octanoic acid (racemic), HPA)

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£273.00

SKU:: 136788
Molekulargewicht:: 182.3
Reinheit:: ~98% (TLC)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
Weitere Details:: Histone deacetylase (HDAC) inhibitor, IC50=13uM (1). More potent and robust than valproic acid at inducing histone hyperacetylation (600% at 50uM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons (2). Cell permeable Solubility: DMSO (~25mg/ml) or Ethanol (~25mg/ml) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.