EX-527, SIRT1 Inhibitor (6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole- 1-carboxamide (racemic))

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£346.00

SKU:: 136777
Molekulargewicht:: 248.7
Reinheit:: ~98% (TLC)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 49843-98-3
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
Weitere Details:: Selective SIRT1 inhibitor (IC50=98nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable. Solubility: DMSO (~18mg/ml) or Ethanol (~10mg/ml) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.