LOXL2 (Lysyl oxidase homolog 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14)

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£709.00

SKU:: 136230
Anwendung:: IHC-Fr
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 15aa from human LOXL2 at N-Terminal.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: LOXL2 is a member of the lysyl oxidase gene family. This family of extracellular, copper dependent enzymes participates in the post-translational modification essential to the biogenesis of connective tissue by deaminating the side chains of lysine residues in collagen and elastin. This results in the covalent cross-linking of fibrillar collagen and the formation of desmosine and isodesmosine cross-links in elastin. Members of the lysyl oxidase family play a role in tumor suppression, cell adhesion and senescence. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin): 15ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.