135002-BIOTIN

UBE2K (Ubiquitin-conjugating Enzyme E2-25kD, Ubiquitin-protein Ligase, Ubiquitin Carrier Protein, E2(25K), Huntingtin Interacting Protein 2, HIP-2, Ubiquitin-conjugating Enzyme E2 K, HIP2, LIG) (Biotin)

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£914.00

SKU:: 135002-BIOTIN
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Full length recombinant corresponding to aa1-40 from human UBE2K with GST tag. MW of the GST tag alone is 26kD.
Klon:: 1D10
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Weitere Details:: HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MLAMSPPAADSYPPPPPPLRPPPPPPPLPPPPPPSAIQT Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.