STK10 (Serine/Threonine-protein Kinase 10, Lymphocyte-oriented Kinase, LOK, PRO2729)

Größe

£685.00

SKU:: 133960
Anwendung:: WB
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Full length human STK10, aa12-145.
Format:: Supplied as a liquid in PBS, pH 7.2.
Weitere Details:: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: FHLRQSLVYVGGGDRGKREAEMFILLLPCFMPSRVPLPAHGCECTHIRVHTGLGLLAWPLLPRWVGTRLLPEPVPLSMLGGAVGVARAGCWHRRHGKAQAVLPGCDACWPPHRLLCAGTDSSAHEASTTQSAP Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.