059373
Interleukin 12 Receptor, Beta 2 (IL-12-Rb2, beta 2 IL-12R-beta-2, IL-12 Receptor beta-2, Interleukin-12 Receptor beta-2 Chain)
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£825.00
- SKU:
- 059373
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Cys28-Asn622 from human Interleukin 12 Receptor beta 2, expressed in NS0 cells.
- Klon:
- 26C8
- Format:
- Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Weitere Details:
- The biological activities of IL-12 are mediated through a high-affinity receptor complex composed of the IL-12 receptor beta 1 (IL-12 Rbeta1) and IL-12 receptor beta2 (IL-12 Rbeta2) subunits. IL-12 Rbeta2 is a 130kD protein that interacts with p35 and is associated with Jak2. The expression of IL-12 Rbeta2 is absent on naïve T cells. Activation of T cells via TCR upregulates IL-12 Rbeta2 expression on human Th1, but not Th2 cells. Applications: Suitable for use in Direct ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice