052804
Nav1.7 Na+ Channel (SCN9A, Sodium Channel Nav1.7)
Größe
£704.00
- SKU:
- 052804
- Reinheit:
- Purified by Protein A affinity chromatography from hybridoma culture.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Fusion protein corresponding to amino acids 1751-1946 (cytoplasmic C-terminus) of human Nav1.7, expressed in E. coli.
- Klon:
- N68/6
- Format:
- Supplied as a liquid in 10mM Tris, 50mM sodium chloride, 0.065% sodium azide, pH 7.3. For antibody without azide, see 052804X.
- Weitere Details:
- Nav1.7 subunit alpha, or SCN9A, is a member of the voltage gated sodium channel family. It is expressed at the terminal ends of sensory neurons in the dorsal root ganglion (DRG) and in trigeminal and sympathetic ganglion neurons. A major function of Nav1.7 is the generation and conduction of action potentials in nociceptors, or “pain receptors” and thus involved in pain sensation. Changes in Nav1.7 expression have been linked to primary erythermalgia, primary erythermalgia, and Congenital insensitivity to pain. Applications: Suitable for use in ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500 Immunohistochemistry: 1:250 Immunocytochemistry: 1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice