Retinol Binding Protein 4, Human

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£607.00

SKU:: 052730
Molekulargewicht:: 21
Reinheit:: ≥95% (SDS-PAGE)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a lyophilized powder in 0.05M Tris chloride, pH 7.4, 0.1M sodium chloride. Reconstitute with sterile ddH2O. For long term storage add a carrier protein (0.1% HSA or BSA).
Weitere Details:: Human Retinol binding protein (RBP) is responsible for binding and transporting retinol (vitamin A). Human RBP has a binding site for one molecule of retinol and circulates in the plasma together with prealbumin in the form of a protein complex in a molar ratio of 1:1. This binding to prealbumin prevents greater glomerular losses of the human retinol-binding protein. Only the retinol-free form of the retinol-binding protein, which has no affinity for prealbumin, undergoes glomerular filtration unhindered as a result of its low molecular weight; Human RBP is re-absorbed by the tubular cells and catabolized there. Source: Human Plasma Molecular Weight: ~21kD Protein: Reported in mg/vial (A280nm, E0.1%=1.86) Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.