5-HT1D (5-Hydroxytryptamine Receptor 1D)

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£812.00

SKU:: 052618
Anwendung:: IHC-Fr
Reinheit:: Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to human 5-HT1D.
Klon:: 25H7 (recomb)
Format:: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
Weitere Details:: Human 5-hydroxytryptamine receptor 1D, or 5-HT1D, is a G-protein coupled receptor for serotonin. 5-HT1D also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation changes in a typical G-protein/adenylate cyclase fashion. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 5-25ug/ml detected 5-HT1D in human brain (substantia nigra) and rat brain Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.