048678
Lysosome Associated Membrane Protein 1 (LAMP 1, CD107a, Igp120, IgpA) (Biotin)
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£371.00
- SKU:
- 048678
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified by affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rat
- Immunogen:
- NIH/3T3 mouse embryonic fibroblast tissue culture cell membranes. It has been mapped to the N-terminus of LAMP-1.
- Klon:
- 1D4B
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin
- Weitere Details:
- CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140kD type I membrane glycoprotein. The mature CD107a is heavily glycosylated from a 40kD core protein. It is expressed by macrophages, epithelial cells, endothelial cells, and some tumor cells. This molecule is located on the luminal side of lysosomes and has been suggested to play a role in the protection of the lysosome membrane from lysosomal hydrolases. CD107a is a ligand for galaptin. Upon activation, CD107a is transferred to the surface of the cell membrane. It plays a role in cell adhesion and regulation of tumor metastasis and mediates autoimmune disease progression. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤1ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice