Serum Amyloid P, Human (Serum Amyloid P-Component, SAP, 9.5S alpha-1-Glycoprotein)

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£563.00

SKU:: 048668
Reinheit:: Purified by Protein G affinity chromatography from tissue culture supernatant.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Native SAP purified from human serum
Klon:: AB18-4E2
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: Serum Amyloid P-component (SAP), also known as 9.5S alpha-1-glycoprotein, is a member of the pentraxin family of proteins. It is synthesized by hepatocytes and secreted into the blood. In humans the levels of SAP range between 20-50ug/ml (Pilling & Gomer 2018). SAP is able to bind to a variety of molecules including apoptotic debris, bacterial polysaccharides, amyloid deposits and bacterial toxins. Phagocytic cells such as monocytes and macrophages then bind the SAP and engulf the material bound to SAP as part of debris clearance (Pilling & Gomer 2018). Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: ELISA: 1ug/ml Optimal dilutions to be determined by the researcher. Matched Pair: Catpure: 048668: Detection: 048669 Hybridoma: SP2/0 myeloma cell line Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.