CD178 (APTL, FASL, FAS-ligand, CD95L, TNFSF6, TNLG1A)

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£479.00

SKU:: 046256
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: L5178Y mouse T lymphoma cells expressing recombinant human CD178
Klon:: NOK-1
Format:: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
Weitere Details:: CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.