TRAIL-R2 (ATTO 488) (TRAIL Receptor 2, DR5, KILLER, TNFRSF10B, CD262)

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£563.00

SKU:: 045354
Reinheit:: >95% (SDS-PAGE)
Lagerbedingungen:: 4°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant human TRAIL-R2 (DR5).
Klon:: HS201
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Weitere Details:: TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. Applications: Suitable for use in Flow Cytometry, Immunocytochemistry Recommended Dilution: Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.