Thiocolchicoside

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£251.00

SKU:: 045336
Molekulargewicht:: 563.6
Reinheit:: ≥95% (NMR)
Lagerbedingungen:: 4°C/-20°C
Hersteller:: United States Biological
CAS Number:: 602-41-5
Format:: Supplied as a yellow solid.
Weitere Details:: Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Weak nicotinic acetylcholine receptor agonist. Muscle relaxant. Anti-inflammatory. Has analgesic properties. Shows strong epileptogenic and convulsant activity. Anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products. Apoptosis inducer. Suppressed osteoclastogenesis induced by RANKL and tumor cells via the NF-kappaB signaling pathway. Therapeutic option for the management of bone metastatic disease. Synonyms: BRN 0072205; NSC 147755; Coltramyl; 10-thio-Colchicoside; 2-Demethoxy-2-glucosidoxythiocolchicine CAS Number: 602-41-5 Source: Semi-synthetic Molecular Weight: 563.6 Molecular Formula: C27H33NO10S Solubility: Water or ethanol. Appearance: Supplied as a yellow solid. Purity: ≥95% (NMR) Storage and Stability: Store at 4°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.