DAPT

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£274.00

SKU:: 044723
Molekulargewicht:: 432.5
Reinheit:: ≥98% (NMR)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 208255-80-5
Format:: Supplied as a white to off-white solid.
Weitere Details:: Cell permeable gamma-secretase inhibitor (IC50 = 115nM for total beta-amyloid, IC50 = 200nM for beta-amyloid 1-42). Reduces Abeta levels in vivo. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). Does not inhibit persenilinase. Notch processing inhibitor. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling. CDK5 activity inhibitor. Apoptosis enhancer. Synonyms: N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine tert.butyl ester CAS Number: 208255-80-5 Molecular Weight: 432.5 Molecular Formula: C₂₃H₂₆F₂N₂O₄ Solubility: 100% ethanol, DMSO (20mg/ml) or dichloromethane Appearance: Supplied as a white to off-white solid. Purity: ≥98% (NMR) Storage and Stability: Store at 4°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.