Bisindolylmaleimide I hydrochloride

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£266.00

SKU:: 044602
Molekulargewicht:: 449
Reinheit:: ≥98% (NMR)
Lagerbedingungen:: 4°C/-20°C
Hersteller:: United States Biological
CAS Number:: 176504-36-2
Format:: Supplied as an orange to red powder.
Weitere Details:: Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Synonyms: GF 109203X; Gö 6850; BIM I CAS Number: 176504-36-2 Molecular Weight: 449 Molecular Formula: C25H24N4O2 . HCl Solubility: DMSO or methanol. Slightly soluble in water. Appearance: Supplied as an orange to red powder. Purity: ≥98% (NMR) Storage and Stability: Store at 4°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.