WHSC1L1, CT (Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3, WHSC1-like protein 1, Wolf-Hirschhorn syndrome candidate 1-like protein 1, Whistle, NSD3, DC28)

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£696.00

SKU:: 043874
Reinheit:: Purified by peptide immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: WHSC1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human WHSC1L1.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Weitere Details:: WHSC1L1 is a histone methyltransferase. This protein preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. Defects in WHSC1L1 may be involved in non small cell lung carcinomas (NSCLC). A chromosomal aberration involving WHSC1L1 is found in childhood acute myeloid leukemia. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.