043481-PE
Txnip, ID (Txnip, Vdup1, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1) (PE)
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£889.00
- SKU:
- 043481-PE
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 116-145 in the central region of mouse Txnip. Species Sequence Homology: rat.
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
- Weitere Details:
- May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Applications: Suitable for use in Western Blot, FLISA and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Formalin fixed, paraffin embedded tissues. Heat induced antigen retrieval with EDTA Buffer, pH 9.0 is recommended. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice