042054-PE
SMPD1, CT (SMPD1, ASM, Sphingomyelin phosphodiesterase, Acid sphingomyelinase) (PE)
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£889.00
- SKU:
- 042054-PE
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 391-419 in the C-terminal region of human SMPD1. Species sequence homology: bovine
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
- Weitere Details:
- The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq]. Applications: Suitable for use in FLISA, Western Blot and Immunohistochemisty. Other potential application, though not tested is Direct Flow Cytometry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (FFPE): Requires HIER using EDTA, pH 8.0 buffer pH9.0 prior to staining. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice