040580-APC
PSTPIP1, NT (PSTPIP1, CD2BP1, Proline-serine-threonine phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP) (APC)
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£889.00
- SKU:
- 040580-APC
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 89-118 in the N-terminal region of human PSTPIP1. Species Sequence Homology: mouse
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
- Weitere Details:
- Proline-serine-threonine Phosphatase-interacting Protein 1 (PSTPIP1) binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. PSTPIP1 appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in the gene encoding this protein are a cause of PAPA syndrome. Applications: Suitable for use in Western Blot, Flow Cytometry (Not Tested) and FLISA. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice