MARH3, CT (MARH3, RNF173, E3 ubiquitin-protein ligase MARCH3, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, RING finger protein 173)

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£696.00

SKU:: 038201
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within 223-251 amino acids from the C-terminal region of human MARH3.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Weitere Details:: MARCH3 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH3 appears to function in the endosomal recycling pathway (Fukuda et al., 2006 [PubMed 16428329]). Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: ELISA: 1:1,000 Western Blot: 1:100-1:500 Optimal dilution determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.