Pin1 (Peptidyl-prolyl cis-trans Isomerase NIMA-interacting 1, PIN1, Peptidyl-prolyl cis-trans Isomerase Pin1, PPIase Pin1, Rotamase Pin1)

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£544.00

SKU:: 031423
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Chicken/Avian
Immunogen:: Recombinant full length Pin-1 purified from E. coli.
Format:: Supplied as a liquid in PBS, 10mM sodium azide.
Weitere Details:: Pin-1 is a the peptidylprolyl cis/trans isomerase enzyme which is responsible, as its name suggests, for flipping the proline ring from the cis to the trans conformation. This enzyme is heavily upregulated in tumor cells, so that antibodies to this protein can be used as tumor markers. Pin-1 protein is concentrated in the nucleus in small punctate structures and is particularly obvious in tumor cells. The HGNC name for this protein is Pin-1. Applications: Suitable for use in Immunocytochemistry, Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilution: Immunocytochemistry (ABC): 1:5000 Immunofluorescence: 1:500-1:1000 Western Blot: 1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.