Pancreatic Polypeptide (PNP, PP, Pancreatic Hormone Precursor, Pancreatic Polypeptide Y, PPY, Pancreatic Prohormone, Pancreatic Prohormone Precursor, HGNC:9327)

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£652.00

SKU:: 030522
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Purified recombinant fragment of human PPY (AA: 1-95) expressed in E. coli.
Klon:: 13B600
Format:: Supplied as a liquid in PBS, 0.05% sodium azide
Weitere Details:: Gene ID: 5539. This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Applications: Western Blot: 1:500-1:2000 Flow Cytometry: 1:200-1:400 ELISA: 1:10000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.