LMO2 (LIM Domain Only Protein 2, Rhombotin-2, LMO-2, Cysteine-rich Protein TTG-2, RBTN2, RBTNL1, RHOM2, T-cell Translocation Protein 2, TTG2)

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£652.00

SKU:: 030399
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. coli.
Klon:: 13B477
Format:: Supplied as a liquid in PBS, 0.05% sodium azide
Weitere Details:: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms. Applications: Western Blot: 1:500-1:2000 Flow Cytometry: 1:200-1:400 ELISA: 1:10000 proposed Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.