Interleukin-10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF, Il10, Il-10)

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£800.00

SKU:: 029517
Anwendung:: WB
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant corresponding to mouse Interleukin-10 fused to GST-tag. Species sequence homology: Human
Format:: Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Weitere Details:: Interleukin-10, originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an18.7kD protein of 160aa residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. IL-10 down regulates the expression of Th1 cytokines, major histocompatibility complex class II antigens, and costimulatory molecules on macrophages. It also enhaces B cell survival, proliferation, and antibody production. Knockout studies suggest that IL-10 is an immunoregulator in the intestinal tract. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.01ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Mouse Interleukin-10 recombinant protein Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.