Tolnaftate

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£377.00

SKU:: 021939
Molekulargewicht:: 307.41
Reinheit:: ≥98%
Lagerbedingungen:: 4°C
Hersteller:: United States Biological
CAS Number:: 2398-96-1
Format:: White to off-white solid
Weitere Details:: Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete′s foot, jock itch, and ringworm. It also has been used as a comparator compound for antifungal efficiency studies. Tolnaftate prevents ergosterol biosynthesis by inhibiting squalene epoxidase. It has also been reported to distort the hyphae and to stunt mycelial growth in susceptible organisms. Tolnaftate inhibits biosynthesis of aflatoxin. Synonyms: N-Methyl-N-(3-methylphenyl)carbamothioic Acid O-2-Naphthalenyl Ester; Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthalenyl Ester; 2-Naphthyl N-Methyl-N-(3-tolyl)thiocarbamate; Aftate; Chinofungin; Dermoxin; Phytoderm; Pitrex; Sch 10144; Tolnaphthate; Tolsanil; Tonoftal; Tritin CAS No: 2398-96-1 Molecular Formula: C₁₉H₁₇NOS Molecular Weight: 307.41 Appearance: White to off-white solid Purity: ≥98% Melting Point: 109-112°C Solubility: Chloroform (Slightly), DMSO (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.