691707
anti-CD74, LN-2, mouse monoclonal antibody
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- SKU:
- 691707
- Zusätzliche Namen:
- HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, Ii, p33, CD antigen CD74 [Cleaved into: Class-II-associated invariant chain peptide, CLIP], CD74, DHLAG
- Anwendung:
- Flow Cytometry, IHC, IF, ICC
- Konzentration:
- 100 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- ABP:
- No Import Docs
- Immunogen:
- Cell extracts from diffuse histiocytic lymphoma SU-DHL-4
- Formulierung:
- PBS with 0.02% sodium azide
- Klon:
- LN-2
- Uniprot:
- P04233, P04441
- Synonyme:
- C;CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated);CD74 molecule, major histocompatibility complex, class II invariant chain;class II-associated invariant chain peptide;CLIP;DHLAG;dinucleotide microsatellite;gamma chain of class II antigens;H-2 class II histocompatibility antigen gamma chain;histocompatibility: class II antigens, gamma chain of;HLA class II histocompatibility antigen gamma chain;HLA-DR antigens-associated invariant chain;HLA-DR-gamma;HLADG;ia antigen-associated invariant chain;Ia-associated invariant chain;Ia-GAMMA;II;ii chain;invariant polypeptide of major histocompatibility complex, class II antigen-associated;MHC class II-associated invariant chain;MHC HLA-DR gamma chain;p33
- Weitere Details:
- LN-2 is directed against the CD74 cluster, established during the IVth Leukocyte Typing Workshops. CD74 comprises four species of proteins (MW 41/35/33 kDa), all coded by a single gene, consisting of nine exons. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. In tissue sections anti CD74 show a binding pattern very similar to that of anti-HLA-DR. It binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. Positive control: Daudi or Raji cells. Tonsil or lymp node.
- Versandbedingungen:
- Blue Ice