691674
anti-MALT1, EBS-T-007, mouse monoclonal antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 691674
- Zusätzliche Namen:
- Mucosa-associated lymphoid tissue lymphoma translocation protein 1, EC 3.4.22.-, MALT lymphoma-associated translocation, Paracaspase, MALT1, MLT
- Anwendung:
- IHC, WB
- Konzentration:
- 100 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Human MALT1 recombinant protein
- Formulierung:
- PBS with 0.02% sodium azide
- Klon:
- EBS-T-007
- Uniprot:
- Q9UDY8
- Synonyme:
- caspase-like protein;IMD12;MALT lymphoma-associated translocation;MALT1 protease;MLT;MLT1;mucosa associated lymphoid tissue lymphoma translocation gene 1;mucosa-associated lymphoid tissue lymphoma translocation protein 1;Paracaspase;paracaspase-1;PCASP1
- Weitere Details:
- EBS-T-007 reacts with paracaspase MALT1, crucial for B- and T-cell activation/proliferation and activation of transcription factor NF-kappaB. It has a N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (BCL10) protein and a caspase-like domain. MALT1 and BCL10 can both be found translocated in MALT lymphoma. In such cases either BCL10 or MALT1 or both are highly expressed, depending on the site of translocation. Normal cells and MALT lymphomas lacking translocations exhibit much lower levels of expression. Positive control: HepG2 cells or lymphoma.
- Versandbedingungen:
- Blue Ice