691613
anti-CD106, B-K9, mouse monoclonal antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 691613
- Zusätzliche Namen:
- Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD antigen CD106, VCAM1
- Anwendung:
- ELISA, Flow Cytometry, IHC, IF, ICC
- Konzentration:
- 100 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Activated umbilical cord vein endothelial cells (HUVEC)
- Formulierung:
- PBS with 0.02% sodium azide
- Klon:
- B-K9
- Uniprot:
- P19320
- Synonyme:
- CD106;CD106 antigen;INCAM-100;vascular cell adhesion protein 1
- Weitere Details:
- CD106 is a protein of 110 kDa, also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100. CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. It is also present on follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. In addition, epithelial cells and cancers cells can be positive, like in kidney and prostate cancer. CD106 serves as a ligand for leukocytes integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. B-K9 inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells. Positive control: human placenta or tonsil, kidney, some prostate cancers.
- Versandbedingungen:
- Blue Ice