691598
anti-CD61, EBS-CD-034, mouse monoclonal antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 691598
- Zusätzliche Namen:
- Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD antigen CD61, ITGB3, GP3A
- Anwendung:
- Flow Cytometry, IHC, IF, ICC
- Konzentration:
- 100 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Stimulated human PBMC's
- Formulierung:
- PBS with 0.02% sodium azide
- Klon:
- EBS-CD-034
- Uniprot:
- P05106
- Synonyme:
- antigen CD61;BDPLT16;BDPLT2;BDPLT24;CD61;GP3A;GPIIIa;GT;GT2;integrin beta 3;integrin beta chain, beta 3;integrin beta-3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61);platelet membrane glycoprotein IIIa
- Weitere Details:
- EBS-CD-034 reacts with a complex of CD41 and CD61, i.e. alpha IIb integrin and the integrin beta chain. The MW of the GPIIIa is 105 kDa unreduced and 90 kDa reduced. The integrin beta 3 chain can also form a complex called the vitronectin receptor with integrin alpha V: the CD51/CD61 complex. Ligands are fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The CD51/CD61 complex is also found on endothelial cells, some B-cells, monocytes/macrophages and tumor cells. Positive control: U937, KG1a, HEL cells, human platelets in lymph nodes or tonsils.
- Versandbedingungen:
- Blue Ice