691586
anti-CD45R0, EBS-CD-027, mouse monoclonal antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 691586
- Zusätzliche Namen:
- Receptor-type tyrosine-protein phosphatase C, EC 3.1.3.48, Leukocyte common antigen, L-CA, T200, CD antigen CD45, PTPRC, CD45
- Anwendung:
- Flow Cytometry, IHC, IF, ICC
- Konzentration:
- 100 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Lentil lectin purified glycoproteins from leucocytes from a B-cell CCL patient
- Formulierung:
- PBS with 0.02% sodium azide
- Klon:
- EBS-CD-027
- Uniprot:
- P08575
- Synonyme:
- B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
- Weitere Details:
- CD45 glycoproteins have various molecular weights on various cell types: B-cell 240 kDa, thymocytes 180 kDa, T-cells multiple bands. Reduced in PAGE gels: 180 and 240 kDa. Relevant epitopes are termed CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45R or CD45R0 (exons 4-6 spliced out). EBS-CD-027 reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B-cells or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK-cells or B-cell lymphomas. Positive control: CCRF-CEM, Jurkat or MOLT-4 cells. Paracortex in tonsil or reactive lymph node.
- Versandbedingungen:
- Blue Ice