691564
anti-CD18, 68-5A5, mouse monoclonal antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 691564
- Zusätzliche Namen:
- Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD antigen CD18, ITGB2, CD18, MFI7
- Anwendung:
- Flow Cytometry, IHC, WB, IF, ICC
- Konzentration:
- 100 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Stimulated human leucocytes
- Formulierung:
- PBS with 0.02% sodium azide
- Klon:
- 68-5A5
- Uniprot:
- P05107
- Synonyme:
- CD18;cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor);Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;complement component 3 receptor 3 and 4 subunit;complement receptor C3 beta-subunit;Complement receptor C3 subunit beta;integrin beta chain, beta 2;integrin beta-2;integrin, beta 2 (complement component 3 receptor 3 and 4 subunit);LAD;LCAMB;leukocyte cell adhesion molecule CD18;leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C;LFA-1;MAC-1;MF17;MFI7;truncated integrin beta-2
- Weitere Details:
- It recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin-2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers. LFA-1, MAC-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54, ICCAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and IC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This Mab blocks these cellular interactions. 68-5A5 was clustered at the IIIrd International Workshop on human leucocyte differentiation antigens. Positive control: human PBL and tonsil.
- Versandbedingungen:
- Blue Ice