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anti-MRP14/S100A9/calgranulin B, 47-8D3, mouse monoclonal antibody

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SKU:: 691519
Zusätzliche Namen:: Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14
Anwendung:: Flow Cytometry, IHC, WB, IF, ICC
Konzentration:: 100 ug/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Progen
Host:: Mouse
Reaktivitäten:: Canine, Human, Porcine, Rabbit, Rat, Caprine, Equine, Feline, Guinea Pig
ABP:: No Import Docs
Immunogen:: Human peripheral blood monocyte components derived by affinity chromatography with Sepharose 4B coupled to rabbit monocyte antibodies
Formulierung:: PBS with 0.02% sodium azide
Klon:: 47-8D3
Uniprot:: P06702, P50116, P50117
Synonyme:: 60B8AG;CAGB;calgranulin B;calgranulin-B;calprotectin L1H subunit;CFAG;CGLB;intracellular calcium-binding protein (MRP14);L1AG;leukocyte L1 complex heavy chain;LIAG;MAC387;macrophage migration inhibitory factor-related protein-14;MIF;migration inhibitory factor-related protein 14;MRP-14;MRP14;myeloid-related protein 14;NIF;P14;protein S100-A9;S100 calcium binding protein A9 (calgranulin B);S100 calcium-binding protein A9;S100-A9
Weitere Details:: 47-8D3 reacts with macrophages and detects the well-known leukocyte L1, a cystic fibrosis antigen. Detecting a single protein band of 14 kDa in Western blots of lysates of human monocytes and granulocytes, the antigen was identified as the calcium-binding protein MRP14, which is a member of the S100 family involved a.o. in regulating the cell cycle. MRP14 is also implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. It is further found on squamous mucosal epithelia. When associated with MRP8 it forms the heterodimer calprotectin. Positive control: monocytes, macrophages, granulocytes.

Versandbedingungen:: Blue Ice