690102
anti-Perilipin 2, AP125, Maus mAk
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 690102
- Zusätzliche Namen:
- Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP, PLIN2, ADFP
- Anwendung:
- IHC, WB
- Konzentration:
- 50 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Canine, Human, Rat
- ABP:
- IMP-GEN-14-02 < 3%
- Immunogen:
- Synthetic peptide (aa 5-27 from N-terminus of human adipophilin/PLIN2)
- Formulierung:
- PBS buffer, pH 7.4 with 0.09% sodium azide and 0.5 % BSA
- Klon:
- AP125
- Uniprot:
- Q5U2U5, Q99541
- Synonyme:
- ADFP;adipophilin;adipose differentiation related protein;adipose differentiation-related protein;ADRP;perilipin-2
- Weitere Details:
- Perilipin 2/Adipophilin/ADRP/PLIN2 is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines; inducible by etomoxir. Enhanced expression of Perilipin 2/Adipophilin/ADRP/PLIN2 is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis. ADRP can also be used to study virus entry via lipid droplets. Polypeptide reacting: Perilipin 2/Adipophilin/ADRP/PLIN2, MW 48,100 (calculated from aa sequence data); apparent Mr 52,000 (after SDS-PAGE); pI 6.72. Immunolocalization: Perilipin 2/Adipophilin/ADRP/PLIN2 is positively detected in the glandular cells of lactating mammary gland (ductal cells are negative), zona fasciculata of the adrenal gland, Sertoli cells of the testis, and in fat-accumulating hepatocytes of alcoholic cirrhotic fatty liver; adipocytes are negative.Also positively stained are lipid-storing CD 68-positive macrophages. Tested cultured cell lines: PLC, MDCK. Learn more about PROGEN Perilipin antibodies.
- Versandbedingungen:
- Blue Ice