61058-488
anti-AAV VP1/VP2/VP3, B1, Maus mAk, AFDyeTM 488
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 61058-488
- Anwendung:
- WB
- Konzentration:
- 500 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Virus
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Immunogen:
- AAV2 capsids
- Formulierung:
- Liquid; PBS + 0.09% sodium azide
- Klon:
- B1
- Weitere Details:
- The B1 antibody reacts with free VP1, VP2 and VP3 of adeno-associated virus (AAV) and at a reduced degree with assembled viral particles. VP1 and VP2 are highly enriched in the nucleus, while non-assembled VP3 is evenly distributed in the nucleus and the cytoplasm. Epitope mapping experiments (Wobus et al., 2000) identified aa726 to aa733 (C-terminus; common to all 3 VP proteins) as the specific binding region. The antibody is also useful for characterization of different stages of infection. The AFDyTM 488 is a green emitting dye, structurally and spectrally equivalent to Alexa FluorR 488 and therefore ideally suited for the 488 nm laser line (excitation/emission 494/517 nm). It can be used with a common FITC filter set. Wobus, C. E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281-93 (2000).Alexa FluorR is a registered trademark of Thermo Fisher Scientific. Limited Use Label License: Research Use Only Product is exclusively licensed to PROGEN Biotechnik GmbH. The use of these products for the development, manufacturing and sale of secondary products/derivatives which are based on the purchased products and/or which include the purchased product require a royalty based sub-license agreement.
- Versandbedingungen:
- Blue Ice