16080
anti-CD44, DF1485, Maus mAk
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 16080
- Anwendung:
- IHC, WB
- Aufreinigung:
- Hybridoma cell culture supernatant
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Progen
- Host:
- Mouse
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Immunogen:
- CD44 antigen (PGp-1) purified from lymphocyte membrane
- Formulierung:
- Contains 0.09% sodium azide
- Klon:
- DF1485
- Weitere Details:
- CD44 (HCAM) is a transmembrane protein expressed by lymphocytes, erythrocytes and several normal epithelial cells and is a member of the CAM family. It is involved in lymphocyte homing, T-lymphocyte activation, interaction with hyaluronic acid and may act as an adhesion molecule. The human CD44 is composed of 19 exons, 9 variably expressed due to alternative splicing of mRNA; standard CD44 (CD44s) is composed of exons 1-5 and 15-19. The loss of CD44s expression predicts unfavorable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinoma and neuroblastomas. In immunoblotting the antibody reacts with a glycoprotein isolated from hematopoetic cells and epithelial cells with a respective molecular weight of 29-37 kD and 51 kD. Positive control: Tonsil (cell membrane staining).
- Versandbedingungen:
- Blue Ice