ICH5016
Atibuclimab Biosimilar - Research Grade
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- ICH5016
- Zusätzliche Namen:
- cluster of differentiation 14
- Anwendung:
- FuncS
- Konzentration:
- 5mg/ml
- Spezies-Reaktivität:
- Human
- Reinheit:
- >95% by SDS-PAGE
- Aufreinigung:
- This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- Lagerbedingungen:
- This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
- Hersteller:
- Ichor Bio
- Reaktivitäten:
- Human
- ABP:
- No Import Docs
- Formulierung:
- Sterile, preservative-free, solution in PBS. BSA and Azide free.
- Uniprot:
- P08571
- Weitere Details:
- RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates a pro-inflammatory cytokine cascade often associated with inflammation in sepsis. Atibuclimab neutralization of this antibody results in the inhibition of TNF-a, IL-6 and IL-10, dampening systemic inflammatory responses. Atibuclimab also delays the release of sTNFR(1) and IL-1ra.
- Versandbedingungen:
- Blue Ice
