200-87
Recombinant Mouse IL-1α / IL-1F1
Größe
£111.00
- SKU:
- 200-87
- Zusätzliche Namen:
- None
- Molekulargewicht:
- 18.1
- Reinheit:
- ≥95
- Quelle:
- E.coli
- Lagerbedingungen:
- Sterile water at 0.1 mg/mL
- Hersteller:
- FujiFilm Irvine Scientific
- Formulierung:
- 10 mM Sodium Phosphate, pH 7.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Spezies:
- Recombinant Mouse
- Uniprot:
- P01582
- Weitere Details:
- Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1α and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
- Versandbedingungen:
- Ambient