200-58
Recombinant Mouse PDGF-BB
Größe
£217.00
- SKU:
- 200-58
- Zusätzliche Namen:
- GDGF, ODGF
- Molekulargewicht:
- 12.4/24.7
- Reinheit:
- ≥95
- Quelle:
- E.coli
- Lagerbedingungen:
- Sterile water at 0.1 mg/mL
- Hersteller:
- FujiFilm Irvine Scientific
- Formulierung:
- 10 mM Sodium Citrate, pH 3.0
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Spezies:
- Recombinant Mouse
- Uniprot:
- P31240
- Weitere Details:
- Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
- Versandbedingungen:
- Ambient