100-56
Recombinant Human OSM
Größe
£217.00
- SKU:
- 100-56
- Zusätzliche Namen:
- Onc-M
- Molekulargewicht:
- 23.8
- Reinheit:
- ≥95
- Quelle:
- E.coli
- Lagerbedingungen:
- Sterile water at 0.1 mg/mL
- Hersteller:
- FujiFilm Irvine Scientific
- Formulierung:
- 10 mM Sodium Phosphate, pH 7.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Spezies:
- Recombinant Human
- Uniprot:
- P13725
- Weitere Details:
- Oncostatin M is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. The Type-I and Type-II Oncostatin M receptors are located on the cell surface of endothelial and tumor cells, contain the glycoprotein 130 (gp130) subunit, and activate the JAK/STAT signaling pathway. Oncostatin M functions to inhibit tumor cell proliferation, induce liver stem cell maturation, regulate cytokine production during hematopoiesis and inflammation, stimulate bone formation, and promote nervous system development.
- Versandbedingungen:
- Ambient
