Intelliscreen[TM] Polycomb Repressive Complex Inhibitors Mini-Library

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£388.00

SKU:: 10-7315
Physischer Zustand:: Supplied as DMSO solution @ 10mM
Lagerbedingungen:: -70[o]C
Hersteller:: Focus Biomolecules
Immunogen:: Chemical Library|Methyltransferase|Ubiquitin ligase
Weitere Details:: The polycomb-group proteins consist of two classes: Polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2). PRC1 acts as a histone methyltransferase primarily methylating H3K27me3 while PRC2 is a histone ubiquitin ligase acting on histone H2A. Both have important roles in epigenetic gene regulation and are implicated in various disease states because of their role in cellular proliferation-differentiation balance, metabolism, and the immune response.