10-5887
Ro 5-3335
Größe
£187.00
- SKU:
- 10-5887
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 259.69
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 30195-30-3
- Immunogen:
- Transcription factor
- Weitere Details:
- Ro 5-3335 was identified in a screen for inhibitors of the RUNX1-CBFB Beta interaction. It represses RUNX1/CBFB-dependent transactivation in reporter assays and runx1-dependent hematopoiesis in zebrafish embryos.1 Ro 5-3335 slows disease progression in various models including acute kidney injury2, acute myocardial infarction3 and osteoarthritis4 among others5. It synergizes with an HDAC inhibitor enhancing the activation of latent HIV-1 in both cell lines and patient PBMCs.6
- Versandbedingungen:
- Ambient