10-5764
Exatecan mesylate
Größe
£158.00
- SKU:
- 10-5764
- Zusätzliche Namen:
- DX-8951f
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 531.56
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 169869-90-3
- Immunogen:
- DNA|Topoisomerase
- Weitere Details:
- Exatecan mesylate is a hexacyclic, water soluble camptothecin analog exhibiting potent antitumor activity in vitro and in vivo.1 It is a potent topoisomerase I inhibitor displaying antiproliferative activity against 32 malignant cell lines and was shown to be 6 and 28 times more potent than SN-38 and topotecan respectively1. It displays potent cytotoxic effects in various drug-resistant cells.2 Exatecan can be utilized as a cytotoxic payload in the development of novel antibody drug conjugates (ADCs).3
- Versandbedingungen:
- Ambient