10-5638
BG45
Größe
£158.00
- SKU:
- 10-5638
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 214.23
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 926259-99-6
- Immunogen:
- Protein deacetylase
- Weitere Details:
- Potent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 mM respectively.1 Inhibits tumor growth in a mouse xenograft model of human multiple myeloma.1 Downregulates expression of DNA methyltransferase 1.2 Increases expression of synaptic proteins in exogenous AB Beta-treated cells and mice.3 Rescues synaptic damage and neuron loss in APP-transfected cells (15 mM) and APP/PS1 mice (30 mg/kg).4
- Versandbedingungen:
- Ambient