10-5589
VE-821
Größe
£177.00
- SKU:
- 10-5589
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 368.41
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1232410-49-9
- Immunogen:
- DNA|Kinase
- Weitere Details:
- VE-821 is a potent and selective ATP-competitive ATR (Ataxia-telangiectasia and Rad3-related protein) inhibitor, Ki=13 nM.1 Increases the sensitivity of pancreatic2 and ovarian3 cancer cells to radiation and chemotherapy. Increased replication stress induced by PARP inhibitors or chemotherapeutic agents increases sensitivity to VE-821 in neuroblastoma cells.4 Enhances the cytotoxicity of DNA damaging agents.5
- Versandbedingungen:
- Ambient