10-5507
CR8 3HCl (R)
Größe
£206.00
- SKU:
- 10-5507
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 540.91
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 294646-77-8
- Immunogen:
- Kinase|Molecular glue
- Weitere Details:
- Second generation analog of roscovitine which inhibits cyclin-dependent kinases with increased potency, Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5, p25, and Cdk9/cyclin T, IC50s=0.09, 0.072, 0.041, 0.11 and 0.18 M respectively.1,2 Acts as a molecular glue degrader that depletes cyclin K.3 CR8 displays neuroprotective effects in various models including traumatic brain injury.4
- Versandbedingungen:
- Ambient